Schisandra fruit 1:2

iBotanical name: Schisandra chinensis
Common name: Schisandra, Magnolia berry, Five-flavor fruit, Magnolia-vine, Chinese magnolia-vine
Plant part: Fruit
Strength: 1:2
Source (Organic or Trade): Trade
Country of Origin: China
Weekly Dosage (mL): 25-60mL 

Actions: Adaptogen, Antioxidant, Hepatoprotective, Nervine

Main indication: Cognitive function, fatigue, sports performance, hepatitis, liver damage

Safety information: Contraindicated in pregnancy.

Drug Interactions: Cyclosporin A - Enhanced oral drug bioavailability reported for low but not high drug dosage in rats
Cytotoxics - Possible enhanced cytotoxic effects by large doses due to reversal of multidrug resistance by gomisin A and schisandrol A
Paclitaxel - Enhanced oral bioavailability of paclitaxel in rats
Rapamycin - Enhanced oral drug bioavailability reported in healthy volunteers
Tacrolimus - Enhanced oral bioavailability shown in healthy volunteers

Article: Schisandra and tacrolimus interaction (2008)